How Cells Move in a Multicellular Organism

Answering the question of how cells move in a multicellular organism is interesting in itself but may also lead to important applications, such as a better understanding of how metastatic cancer actually spreads. Researchers at NIH, Rochester, and Penn State, have identified a new way for cells to move inside a three-dimensional matrix: by using the cell nucleus as a piston! The research was published in Science at the end of August. For more information, see the BioTechniques news story entitled The Nucleus Is a Piston and the Science perspective entitled Many modes of motility.